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1973-01-01 · THE STRUCTURE OF SALINOMYCIN, A NEW MEMBER OF THE POLYETHER ANTIBIOTICS Haruyasu Kinashi, Noboru Stake and Hiroshi Yonehara Institute of Applied Microbiology, The University of Tokyo Shoichi Sato and Yoshihiko Saito Institute for Solid State Physics, The University of Tokyo Tokyo, Japan (Received in Japan 3 October 1973; received in UK for publication 29 October 1973) Salinomycinl is a new antibiotic elaborated by the strain of Streptomyces aZbus and has an antimicrobial activity Salinomycin sodium | C42H69NaO11 | CID 23703990 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. Salinomycin' is a new antibiotic elaborated by the strain of Streptomyces aZbus and has an antimicrobial activity against Gram-positive bacteria, mycobacteria and fungi. Furthermore, salinomycin is effective in the treatment of coccidial infections in poultry. In light of its biological activity coupled with the physicochemical properties and spectral data, the antibiotic is assumed to belong This information is only displayed if the substance is well-defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure. More help available here. EC / List no.: 258-290-1.

Salinomycin structure

2017-03-28 · Salinomycin blocked Wnt signaling and downregulated ZEB1, thereby increasing the sensitivity of MCL cells to the cytotoxic effect of gemcitabine, cytarabine, and doxorubicin. 70 In combination with metformin, salinomycin was able to block TGFβ-induced EMT and inhibit EMT-induced cell migration in the two non-small-cell lung cancer cell lines A549 and HCC4006. 71 Salinomycin inhibited File:Salinomycin-structure.png. From Wikimedia Commons, the free media repository. Jump to navigation Jump to search.

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Hi there friends Growing evidence suggests that salinomycin is able to kill different types of perceived as correct at that time; mediation through the anatomical structure. 30 mars 2021 — molecule model and chemical formula. Organic chemical compound.

Learn more about Salinomycin and get the best prices in the life science marketplace at Salinomycin chemical structure | CAS 53003-10-4 | AG Scientific, Inc. A series of 12 novel monosubstituted N-benzyl amides of salinomycin (SAL) was Molecular structures of three salinomycin derivatives in the solid state were For research use only. We do not sell to patients. Salinomycin sodium salt Chemical Structure. CAS No. : 55721-31-8 I. The Crystal and Molecular Structure of Salinomycin p-Iodophenacyl Ester. BY HARUYASU KINASHI, NOBORU OTAKE AND HIROSHI YONEHARA Institute of The ability of salinomycin to kill both CSCs and therapy-resistant cancer cells may structure of salinomycin was determined by X-ray crystallographic analysis, Salinomycin | C42H70O11 | CID 3085092 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, 15 Jan 2021 This curcumin and salinomycin co-delivery system can be an efficient treatment Solid-state and solution structure of the salinomycin–sodium Visit ChemicalBook To find more Salinomycin(53003-10-4) information like chemical properties,Structure,melting point,boiling point,density,molecular formula is to present an overview of their formula, molecular structure, and properties. 1.
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S4526. from Streptomyces albus, ≥98% (HPLC) Sigma-Aldrich. Structure, properties, spectra, suppliers and links for: Salinomycin sodium. Salinomycin is an antibacterial and coccidiostat ionophore therapeutic drug. Salinomycin has been shown by Piyush Gupta et al.

Salinomycin inhibits proliferation and induces apoptosis of human Conclusions: Synthetic structural analogs of salinomycin, previously shown to exhibit The Molecular Basis for Inhibition of Stemlike Cancer Cells by Salinomycin | ACS Chemical modification and structure-activity correlation of salinomycin. To visualize cellular uptake and subcellular localization of salinomycin, we sought a fluorescent conjugate that was functionally equivalent to the native structure. An active fluorescent salinomycin conjugate reveals rapid cellular uptake and a fluorescent conjugate that was functionally equivalent to the native structure. Conclusions: Synthetic structural analogs of salinomycin, previously shown to exhibit Chemical modification and structure-activity correlation of salinomycin.
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The structure of salinomycin, a new member of the polyether ant ibiotics. Kinashi H. Tetrahed. 2016-03-01 For a structural comparison, salinomycin·Na, SY-1·Na, and 18,19-dihydro SY-1·Na were modeled using the X-ray structure of SY-1·Na as the initial geometry.

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The RCSB PDB also provides a variety of tools and resources. Users can perform simple and advanced searches based on annotations relating to sequence, structure and function.

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Salinomycin has been shown by Piyush Gupta et al.

Crystal structure of salinomycin allyl amide acetonitrile solvate. The relative affinity of salinomycin for complex formation with various cations decreases in the order K + > Na + > Cs + > Sr 2+ > Ca 2+ , Mg 2+ . The monocarboxylic polyether ionophore salinomycin (1, Fig. 1) has found wide-spread commercial use in veterinary medicine as a coccidiostatic agent and non-hormonal growth promoter.